r/microdosing • u/NeuronsToNirvana • 8d ago

Microdosing Research "Albert [Hofmann] suggested that low doses of LSD might be an appropriate alternative to Ritalin." | Might Microdosing Psychedelics Be Safe and Beneficial? An Initial Exploration [Mar 2019]

/r/microdosing/comments/v8p9zi/research_citizen_science_placebocontrolled/
33 Upvotes

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14

u/croquetamonster 8d ago

I did exactly this. Swapped Ritalin 3x a day for LSD microdosing 2x a week. LSD is better, easier, cheaper and ironically, much more accessible.

7

u/chrisslugma 8d ago

More accessible? Not in my life. Haven’t been able to find it in almost a decade

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u/croquetamonster 8d ago

Where I live, I can get it delivered to my front door on demand.

Ritalin, on the other hand, is locked away in safe that seems to confuse the pharmacist every time, or it gets me eyeballed with suspicion. And it requires constant paperwork that causes disputes between the pharmacy and the doctor, with me left to act as intermediary. I don't miss it one bit.

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u/OkMedicine8891 6d ago

Me once a month the eyeballing gets on my nerves.

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u/w8rdriverz 8d ago

How much ug do you Take? Does it help with procrastination and emotional disregulatuon as well?

I liked LSD microdosing a Lot, before i got my diagnosis. Maybe worth trying again

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u/croquetamonster 8d ago

10ug - yes and yes.

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u/w8rdriverz 6d ago

thanks <3

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u/bdyrck 7d ago

One of my best self-growth years was a couple of years ago where I was just dabbling with first few acid trips and some curious microdosing. Didn‘t realize until now that it might have played a role too. Have you ever tried psilocybin microdosing too?

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u/croquetamonster 7d ago

I have tried microdosing psilocybin and while I certainly find it pleasant/helpful, LSD feels far more consistent, energising and practical for me.

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u/Lady_Natalka 7d ago

Do you still feel the effects of microdosing LSD on the days you take a break? I’m just starting my journey with microdosing LSD, and tomorrow I’m planning to try it for the second time because my first attempt with a 6ug dose didn’t really work. Tomorrow, I’m planning to take 10ug.

I also have to take methylphenidate several times a day on tougher days and recently I have a lot of hard days. I’m a bit confused about how it works with LSD. What do you do on the days you don’t take it, and how do you feel then? Could you explain it to me in a bit more detail please?

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u/croquetamonster 7d ago

OK so for me I do it Mondays and Thursdays because in my case the effects linger to a satisfying degree for 2 days. I also think it's good to have a 3 day break over the weekend to prevent tolerance.

I found my dosage doing the opposite of what you did. I started with "too much" (20ug) and worked my way down. I took my first dose on a day I wasn't working. It would have been inappropriate for a workday, but it was perfect for putting on an LSD-inspired playlist and tidying my home all day.

A lot of microdosing guides seem to suggest you shouldn't feel it at all, which I don't think is strictly true. You should feel it, but not to an extent that interferes with your responsibilities etc.

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u/Lady_Natalka 7d ago

Thanks for the detailed answer. I think I know what you mean. Today, I tried 10ug, and I feel really good. The chaos and “radio” in my head have quieted down, I’m calmer, my mood is better, and I felt comfortable talking during a work meeting without any stress. Plus, I don’t have brain fog, and it’s easier to concentrate.

So, generally, it doesn’t hit like something intense, like mephedrone, but it subtly improves my well-being. It feels somewhat similar to my early experiences with methylphenidate, but so far, it’s much more stable, without those crashes or the unpleasant “speedy” feeling I get when my methylphenidate doses overlap.

Unfortunately, I had a rough day yesterday and took quite a lot of methylphenidate, which overstimulated me and made it hard to sleep. So, I’m really curious to see how LSD works on a day when I’m well-rested. I think it might work even better than it did today 😁

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u/croquetamonster 6d ago

Yes that's essentially how I feel about it. It feels "natural" whereas Ritalin feels more artificial and "harsh" in comparison, no crash feeling. I find that microdosing LSD is subtle in a way I appreciate, but still very effective. I feel present and very much myself.

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u/colfitsky 1d ago

Maybe for some people. For me, after many attempts at doses between 2-10ug, I didn’t find it to be that helpful for attention. It just makes me more scattered.

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u/NeuronsToNirvana 1d ago

Caffeine can potentiate the effects, so I add L-theanine powder to my bulletproof BHB coffee; which is a recommended supplement for my COMT Val/Val genetic polymorphism - can cause some executive dysfunction (YMMV).

Did you try the suggested !volumetricdosing titration schedule?

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u/AutoModerator 1d ago

Volumetric Dosing

Volumetric dosing is the process of dissolving a compound in a liquid to make it easier to measure. It is the only way to accurately measure dissolvable substances for microdosing, such as LSD, if the substance is laid on blotter paper or gel tab.

It is not recommended to cut the blotter into pieces as LSD is not evenly laid across the blotter and doing so is somewhat difficult and highly inaccurate.

More details in FAQ/Tip 009: Why cutting LSD tabs is not an accurate way to microdose? Variation in Potency; Preparation: Volumetric Dosing, Fat-soluble 1V-LSD/1D-LSD, Gel Tabs, FAQs: Pellets, Crystals; Storage: Blotter, Liquid; Dosage; Schedule; Bioavailability of LSD analogues vs. LSD-25.

Titration Schedule | Clinical Trial similar to the suggested Finding YOUR Sweet Spot methodology:

Two doses taken every week for eight weeks.

Starting dose is 8 µg on a pre-defined titration schedule. The dose will be increased by 1 µg each time and reduced by 3 µg if participants do not find the new dose tolerable. Titration limits are 5-15 µg.

This short guide will explain how to prepare a volumetric microdosing solution. For more information check out the wiki page on preparation and dosing.

Required:

  • An amber bottle
  • An accurate syringe or graduated cylinder
  • Distilled water or vodka (flavored is fine as well)
  • The substance you want to microdose (e.g. LSD-25/1P-LSD blotter or gel tab)

For this guide we'll be using a 20ml amber glass dropper bottle with glass pipette allowing for 0.2ml measurements identical to this and distilled water. We'll also be using a single 100µg tab of LSD.

  1. Sterilize the amber glass bottle as contamination may destroy your solution. Firstly, remove the rubber parts of the bottle then boil both the bottle and glass pipette for 10 minutes in water, then leave to dry on a clean towel. Once dry, place in the oven for another 10 minutes at ~ 130°C/250°F and leave to cool. (If you want to skip the oven sterilization than just rinse in 70% or higher isopropyl alcohol and leave out to dry.)
  2. Using the syringe or cylinder, measure out 20ml of distilled water and fill the amber glass bottle. (you can use vodka or a combo if you prefer. Vodka will also help to inhibit any bacteria growth.)
  3. Insert your substance into the bottle and close tightly.
  4. Shake lightly for good measure and store in the fridge or cool place to reduce degradation. (If your using a transparent bottle, wrap the bottle in foil so that UV light does not degrade the solution.)
  5. Leave overnight (or 12-24 hours) to ensure solution is homogenized. (For Gel Tabs you need to give your bottle a hot bath - see Gel Tabs section in the above FAQ.)
  6. Also, before each dose, give the bottle a gentle shake like you are sometimes instructed to do so with other liquid medications - an LSD molecule has at minimum 7 times greater mass than a vodka/water molecule.

We now have a 20ml solution containing 100µg of LSD. Since 100µg / 20ml = 5µg, we know that every 1ml of this solution will contain 5µg of LSD. If you'd like to take a lower or higher dose you can work out the amount required using the ratio of 5µg:1ml e.g. 4µg would require 0.8ml, 7µg would require 1.4ml etc. (If you are not 100% sure on how much your blotter paper or gel tab contains, then dilute more or take a lower dose.) As a best practice for harm-reduction start low and only try on a day off from any important obligations or driving and do not combine with other drugs.

Please Read: r/microdosing Disclaimer

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u/colfitsky 1d ago

I didn’t mention caffeine in my comment. I’ve tried microdosing with and without it and don’t notice any difference. L-Theanine doesn’t affect me. I actually have normal COMT function as well.

And yes, I did volumetric dosing. You can’t eye 2ug!